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Biotech Pilot Suite

Biotech Pilot Suite - Projects - Ridge & Partners LLP

The £15 million biotech pilot suite is for the production of Good Manufacturing Practice toxin materials for clinical trials and commercial launches. The toxin materials are within closed microbiological safety cabinets and the processes carried out here include bioreaction, chromatography and tangential flow filtration.

A high level of precision was required for the construction of this minutely-controlled, state-of-the-art environment. Ridge professionals guided the client through a complex procurement process to deliver this ambitious project to the highest standards and within budget.

A Grade C clean room (Grade A within MBSC) was constructed to a CL3 Bio-security level.  The facility comprises:

  • Main process suites including seven MBSCs with PPC sealed extract
  • Dedicated process utilities (including WFI, DI Water, pure steam and compressed air) housed within a new extension, which included IQ, OQ and PQ protocols
  •  New toxin development laboratory
  • Quality control facilities.

Ridge undertook an intensive cost planning exercise based on the latest design for the facility to challenge the capital expenditure forecast and ensure scheme met the required standards while remaining within budget.  Ridge professionals also validated earlier estimates for direct costs, equipment and C&Q.

Ridge advised the client on the options regarding contractual frameworks and procurement routes and guided the client through the nuances of the iChemE form of contract.  Ridge selected the Target Cost version of the contract and, based on our deep experience in this sector, proposed a formula to incentivise the contractor successfully.

Biotech Pilot Suite - Projects - Ridge & Partners LLP

Biotech Pilot Suite - Projects - Ridge & Partners LLP

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Biotech Pilot Suite - Projects - Ridge & Partners LLP

Biotech Pilot Suite - Projects - Ridge & Partners LLP

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Biotech Pilot Suite - Projects - Ridge & Partners LLP

Biotech Pilot Suite - Projects - Ridge & Partners LLP

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